Calcitonin (also called thyrocalcitonin) is a 32-amino acid linear polypeptide hormone which is mainly by the parafollicular cells (also known as c-cells) of the thyroid gland, and by the many other animals in the ultimopharyngeal body Is produced. It works to reduce blood calcium (Ca2 +), while opposing the effects of pterothyroid hormone (PTH).
Calcitonin has been found in fish, reptiles, birds and mammals. Its importance in humans is not well established in other animals as its importance, because its function is usually not important in the regulation of normal calcium homeostasis. It belongs to the calcitonin-like protein family.
Calcitonin is a hormone produced in human beings by the thyroid gland’s parafollicular cells (usually known as c-cells). Calcitonin is involved in helping control the level of calcium and phosphate in the blood, opposing the action of parathyroid hormone.. This means that it works to reduce the level of calcium in the blood. However, the importance of this role in humans is unclear, because such patients who have very low or very high levels of Calcitonin do not show any adverse effects.
Calcitonin Reduces Calcium Levels In Blood By Two Main Mechanisms:
1. This prevents the activity of osteoclasts, which are the cells responsible for breaking bones. When the bone breaks, the calcium contained in the bone is left in the blood stream. Therefore, obstruction of osteoclasts by Calcitonin directly reduces the amount of calcium released in the blood. However, this barrier has been shown short-term.
2. It can also reduce calcium rehabilitation in the kidney, which reduces low blood calcium level. Read More
2. It can also reduce calcium rehabilitation in the kidney, which reduces low blood calcium level. Read More
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